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Article No.: A2650
Articlename: PurityChrom® Basic

PurityChrom® Basic

Basic License: 8 devices, 3 data channels, no autosampler supported

PurityChrom is a chromatography software specially designed for the area of preparative purifications and FPLC applications. 
PurityChrom provides a user-friendly and clearly structured interface. The system visualization offers a graphical representation of the purification system and allows easy handling even of complex flow processes. Furthermore, each device that is displayed in the fluidic scheme can be manually controlled, giving the opportunity to optimize, change and adapt your conditions during the run. Due to its high flexibility, methods can be developed according to specific demands.
You have the option to create a method based on volume, column volume, or time. There is also a possibility to pause or to change the method parameters during the run, which gives you complete control over your chromatography process. In PurityChrom you can define important functions in your method with variables. This allows you to write methods that can be adapted more flexibly to a specific sample or column, just before the run with only one click. In combination with the sequence table, a quick and easy method scouting provides you with the best method for your purification problem in less time. Furthermore, the sequence table helps to automate purification and CIP protocols.
For fractionation, you can use a fractionation valve as well as a fraction collector.
The function Solvent Supply calculates the consumption of solvent for the current run and prevents your column from running dry whereas the function Waste Management prevents the loss of your sample.
Current guidelines and regulations like 21 CFR part 11 are considered in the software. Accordingly, an user administration and an audit trail is implemented. PurityChrom allows flexible support of different devices from KNAUER and other manufactures. Please check for more information about supported devices the Release Notes of the latest PurityChrom version. With an unlimited number of free offline licenses, you can write methods and evaluate runs on any computer of your choice, without blocking the system. Furthermore, we offer free updates for PurityChrom MCC Plus as well as a demo license that can be used to get a first impression of the software user interface. 
The basic version offers all main features but is limited to 3 data channels and the control of eight devices, but does not support an autosampler. The upgrade version (A2652) supports 8 data channels and an unlimited number of devices including an autosampler. The 3D option (A2654) allows the support of a diode-array detector and the MS option (A2655) the usage of a mass spectrometer.

Key Features

Technical Data


Software name PurityChrom® 5
Extensions / Licenses PDA / 3D UV, Mass spectrometry
Operating system Windows XP, Windows Vista, Windows 7, Windows 8, Windows 10 (English or German only)


Stand-alone License for controlling one system
Multi-user environment Optional user administration with individual assignment of rights for individual users
Fields of applications FPLC & Prep LC
Instrument connection supports RS-232, Ethernet, A/D-D/A interface
Recommended PC hardware CPU/Memory: Pentium III or higher with at least 1 GHz; 32 or 64 bit; at least 512 MB RAM (Windows XP) and 2 GB (Windows Vista and higher)
Second network card is required for network integration
Graphics: Screen with minimal resolution 1024 x 768
Connectors and Slots: USB for license dongle; COM, USB or LAN according to connected instruments
Integration Real-time analysis of peaks, automatic or manual integration and baseline correction
Security and GLP FDA 21 CFR Part 11 conformance
Automation via sequences and autosampler control files
Presentation of results Individual report configuration as pdf or csv
Calculations Column performance calculations according to DAB
Data import and export Comma Separated Value, AIA/ANDI, ChromStar Slice
Special features Method creation based on time, volume or column volume; hold function; functionalized visualisation; direct control during a run; display of solvent supply; usage of variable values

Additional options/extensions

FRC option Included
FRC features Control of fraction collectors and KNAUER valve drives as fractionation valve, fractionation per Time/Level/Slope, rack info with filling level and chromatogram link
PDA option special licence option; no 3D presentation
Note For autosampler control the upgrade licence is needed

Documents and more information

Certified Quality 

KNAUER is known for the quality of its products and has been certified several times. We produce high-tech laboratory instruments for research, routine analysis and production.
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In addition, we have extended documentation about all our products, including CE Declarations of Conformity.
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