HPLC & UHPLC detectors from MS/MS to UV and beyond ...

KNAUER gives you the opportunity to analyze nearly every compound due to a large portfolio of HPLC detectors and detection principles.
  • Spectrophotometry of UV & visible light
  • Refractive index detection (RI), refractrometry
  • Fluorescence detection, fluorimetry (FL)
  • Evaporartive light scattering detection (ELSD)
  • Mass spectrometry (MS)
  • and more ...
For achieving your analysis goals and for matching your separation scale, our HPLC detectors are flexibly adjustable, including choices of flow cells, fiber optics, and nebulizers. With outstanding sensitivity, stability and usability the HPLC detection systems offered by KNAUER match your everyday challenges. KNAUER HPLC detectors can be integrated into nearly every HPLC system to match your specific requirements and can be operated with a broad range of software packages.

Please contact us for further information.

High-performance LC-MS/MS mass spectrometry solutions

Triple Quad™ 3500 and 4500 MS/MS systems

These SCIEX Triple Quad MS/MS systems provide the productivity, reliability, and robustness required for today’s analytical laboratories for quantitation of hundreds of compounds in hundreds of samples – day after day, year after year.

These MS detection systems allow quantification of acidic, neutral and basic analytes in one shot. The compact SCIEX triple quad design saves you valuable bench-space.

The Triple Quad 3500 offers expert level performance at an entry level price. The Triple Quad 4500 enables even higher sensitivity and performance for the most demanding analytical applications.

Sensitive UV/VIS detectors

We provide a choice of UV/VIS detectors, ranging from single variable wavelength to 8-channel diode array detector with LightGuide total reflection technology.
The AZURA DAD 6.1L is equipped with revolutionary KNAUER Polka-Dot technology providing maximum light intensity and low noise over the whole UV/VIS spectrum. This technology provides more light than previous shine-through lamp configurations.

Both AZURA diode array detectors DAD 6.1L and DAD 2.1L provide high spectral resolution enabling optimized identification and sample characterization.

Sensitive – LightGuide flow cells and Polka-Dot technology
Accessible – easy lamp and flow cell exchange from the front
Flexible – wide range of flow cell for high application versatility
Robust – intelligent temperature control for minimal drift

AZURA® UV/VIS Detector

UVD 2.1S

UVD 2.1L

MWD 2.1L

DAD 2.1L

DAD 6.1L


Compact and versatile UV detector

Reliable UV/VIS detector for a wide spectrum of applications

Robust multichannel UV/VIS detector

Versatility through a wide flow cell range

High-end diode array detector with outstanding performance

Wavelength range (nm)






Channels 1 1 8 8 8
3D data acquisition       + +
Data acquisition rate* 50 Hz 50 Hz 100 Hz 100 Hz 100 Hz
Fiber optics available + + + + +
LightGuide flow cells     + + +
PressureProof flow cells     + + +
Biocompatible**  flow cells + + + + +

Do you need more information or a quote? We are happy to help you!

*| sampling rate,  **| bio-inert

Which flow cell suits your application best?

HPLC with remote UV/VIS detection

KNAUER fiber optics technology offers the possibility to separate the flow cell spatially from the detector via fiber optic cables in a distance up to 10 meters. This enables the measurement of UV/VIS absorption in flow-through mode remotely from the detector.

Fiber optics enable the flow cell to be located very close to the column, minimizing peak broadening.

The UV nano flow cell with fiber optics technology from KNAUER received the Best of Industry award 2017.

Remote UV/VIS flow cells with fiber optic connectors

refractive index (RI) detector for LC

Detection of small amounts of dissolved compounds with little or no absorption in the UV/Vis spectral range represents an analytical challenge even today. The differential refractometer is an established work-horse for the cost-effective detection of alcohols, sugars, lipids or polymers in HPLC (high performance liquid chromatography) and GPC (gel permeation chromatography).

No chromophor? No problem.
MEET the AZURA RI Detector 2.1L

refractive index detectors

A wide range of third-party lc detectors can be seamlessly integrated into AZURA analytical systems

See the complete KNAUER LC Detector portfolio


Our complete HPLC/UHPLC brochure is available as a PDF.

We are happy to support you

Any questions about our products, solutions and services?
Need a quote?

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