Freezing Point Osmometer

KNAUER is one of the pioneers in the field of osmometry and known for its reliable and user-friendly instruments for many decades. Our newest freezing point osmometer K-7400S allows the easy and fast determination of the osmolality of various aqueous solutions. Also, the freezing point depression of the samples can be read.

The proven technology of freezing point determination in combination with the robust and intelligent design of the device allows fast and reproducible measurements. The instrument is equipped with a peltier cooler and an integrated microprocessor controlling the automated measurement.

Learn more about the theory of osmomality and osmometry below!

more about osmolality 

Quality control of pharmaceutical solutions by determination of osmolality

The osmolality of solutions used in the clinical and pharmaceutical field is an important issue that requires regular monitoring. Especially infusion solutions but also solutions for external use like eye drops and rinsing solutions must be isotonic to ensure the physical well-being of humans. In this study, the osmolality of commercially available pharmaceutical solutions were determined using the KNAUER K-7400S Semi-Micro Osmometer.

Determination of osmolality of isotonic and non-isotonic beverages

In the last years isotonic beverages have become more and more popular. Almost every drink is available in an isotonic version. But what does isotonic mean and what are its benefits? How can you check that beverages are really isotonic? And how is osmolality involved?

Osmometer Reviews

In many laboratories, the accurate concentration of solved molecules in a liquid is essential for daily work routine. The KNAUER K-7400S Semi-Micro Osmometer is ideally suited for this task, since most solutes in a liquid can be measured. The determination of total particle concentration or osmolality becomes fast and simple. KNAUER is one of the pioneers in the field of osmometry and is known for its reliable and user-friendly instruments for many decades.

Get your osmometer care-free package

Order the KNAUER osmometer care-free package today and start your osmolality measurements "tomorrow".

When ordering the Freezing Point Osmometer (order no. A0006C) you will receive everything you need to start measuring the osmolalities of your aqueous solutions right away. With our care-free package you will be able to install your osmometer and start the measurements fast and easily. Detailed instructions as well as online video tutorials will support you with every question you might have.

Osmolalities of the world

We analysed water around the world to create the first osmolality world map


Would you like to take part in creating the first osmolality world map? Send us your sample!

Regardless if there is the sea, a lake, a pond or a river right at your doorstep – just send us a small sample of it (1 ml in a sample tube). We will analyse it for you and add it to our map. Please take care to not use a vessel made of PE to store your sample, since this can render the sample impossible to analyze.

Send your sample to:

- Osmometry sample -
Hegauer Weg 38
14163 Berlin



EuroOsmo 7400 control software

The K-7400S Semi-Micro Osmometer is a standalone device. Therefore, all functions of the instruments are accessible via the keypad. For additional storage and data management functions users can work with the EuroOsmo 7400 software. It offers a user-friendly interface to control the K-7400S Semi-Micro Osmometer via PC.

Measurement parameters can easily be changed and sent to the instrument via the software. For each sample a temperature curve is displayed to visualize the measurement process. Samples can be named individually and the measurement results can be saved for archiving. The data can also be exported in different file formats (e.g. *.xls, ASCII or Tab delimited text files). Thus, also the import to laboratory information management systems (LIMS) is possible. Supporting the use of a barcode scanner, sample identification can be transferred automatically reducing the risk of wrong sample assignment.

We have prepared a series of video tutorials on EuroOsmo 7400. Check them out here.

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