Let your application define your system solution.

In HPLC, components of a mixture are carried through the stationary phase by the flow of a mobile phase and separation is based on differences in migration rates among the sample components. Therefore, the nature of your analytes defines not only the method but also the HPLC system.

Main characteristics of the analytes:

MOLECULAR WEIGHT defines the pore size of the stationary phase

SOLUBILITY defines the HPLC mode, chemistry of stationary phase and eluent.

CONCENTRATION AND MATRIX define the detection parameters and column dimensions.

The solubility of your analytes defines the HPLC mode. The elutropic series defines the solvent strength for the most often used chromatography modes normal phase and reversed phase.

Analytical HPLC/UHPLC system

Efficient and adaptable to your needs

Flow chart of an analytical HPLC system

The analytical HPLC and UHPLC systems of the KNAUER AZURA liquid chromatography instruments are designed to support and facilitate your work. Whether doing routine analysis or demanding separation tasks, AZURA systems are the right tool to overcome your analytical challenges. Choose between different gradient forming technologies and maximum flow rates to find the best configuration for your task.

AZURA® Analytical HPLC systems

More Analytical HPLC systems


Configure your perfect (U) HPLC system

Build a custom solution based on your requirements. Choose the system components you need. We create an individual system for you. Chromatography by KNAUER!

HPLC Basics –
Principles and parameters

Liquid chromatography is a well-established technique for the separation of substances. High performance liquid chromatography (HPLC) is a suitable method for the analysis of a wide range of application areas. Here, we describe the principle of HPLC and introduce to the most important components in an HPLC system and the factors that determine the success of a measurement.

Application areas


Discover the wide range of possible applications.

View the complete AZURA analytical brochure

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