For more than 40 years, liquid chromatography columns from KNAUER have been well-known for their high quality and performance.

In the field of analytical HPLC columns we can offer a solution for nearly any analytical separation task. KNAUER offers about 6,000 columns for analytical HPLC and UHPLC applications as well as for purification tasks in the preparative scale.

KNAUER LC column brands

  • Eurospher 
  • Eurospher II
  • Eurosil Bioselect
  • Eurokat
  • Eurospher I: the HPLC columns for every day                                 

    Suited for a wide range of analytical, semi-preparative and process scale separations in normal phase and reversed phase mode.

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  • Advanced HPLC / UHPLC columns: Eurospher II

    Eurospher II is introduced as the new workhorse for an even wider range of application areas, suitable for analytical, semi-preparative and process-scale separations. The logical choice to take on routine analyses as well as the most ambitious chromatoraphy tasks

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  • HPLC columns for bioanalytics: Eurosil Bioselect

    Eurosil Bioselect columns feature a wide-pore stationary phase and were specifically designed to separate large biomolecules such as proteins and peptides.

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  • HPLC columns for food analysis: Eurokat

    Eurokat columns are valuable for food analysis and especially developed for the separation of organic acids, carbonhydrates, alcohols and even complex mixtures of these compounds.

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(U)HPLC of small molecules

Silica gel based KNAUER columns for HPLC and UHPLC in the most often used modes

HPLC of sugars, organic acids and alcohols

Ion exclusion and ligand exchange columns

Based on a sulfonated cross-linked styrenedivinylbenzene copolymer and available in several ionic forms (H, Ca, Pb and Ag). This particular cation exchanger is characterized by an outstanding density of functional groups, making it the ideal choice for your ion exclusion, size exclusion and ligand exchange chromatography.


HPLC of Biomolecules

Analytical wide pore HPLC columns

The use of larger pore silica-based bonded phases leads to improvements in resolution, capacity and recovery of proteins and other biomolecules, due to a reduction in size exclusion mechanism and enhanced molecular diffusion rates. A pore size of 300 Å has become the accepted standard for wide pore silica gels because it has been found to be suitable for a broad range of molecular weight proteins, peptides and oligonucleotides. In general, peptides exceeding approximately 50 amino acids and oligonucleotides greater than 25 residues are preferentially analyzed on 300 Å materials.


SEC and GPC Columns

Preparative HPLC Columns

Preparative KNAUER columns for HPLC can be offered with two different hardware types:


Available preparative column dimensions:

hplc / uhplc column selection  guide

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