High performance UHPLC pump with binary gradient

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Article No.: APF45PA
Articlename: AZURA P 8.1L

High performance UHPLC pump with binary gradient

AZURA® P 8.1L UHPLC pump suitable for ultra-fast and high-resolution applications

The new AZURA® P 8.1L UHPLC pump offers a maximum delivery pressure of 124 MPa/1240 bar and a flow rate range up to 5 ml/min for ultra-fast and high-resolution applications.


The adaptive pulsation compensation of the pump is independent of flow rate, backpressure, and eluent type through real-time eluent compressibility monitoring and variable piston stroke. Together with the ultra-precise piston movement thanks to KNAUER’s proprietary advanced piston drive technology, this results in outstanding flow reproducibility at any working conditions. The pump also features a 2-channel internal degassing unit, a 2x2 channel solvent selection valve, and a low dwell-volume eluent mixer.


Developed with innovative technology and decades of continuous improvements the AZURA® P 8.1L UHPLC pump enters a new level of performance and durability. With a high level of in-house component production KNAUER achieves an industry-leading level of manufacturing precision. This results in unmatched piston seal life and system uptime.

Technical Data

General information

Max. flow rate 5 ml/min
Flow rate range 0.001–5 ml/min
Flow rate increment 0.001 ml/min
Maximum delivery pressure [psi] 18000 psi
Maximum delivery pressure [MPa] 124 MPa
Maximum delivery pressure [bar] 1240 bar
Pump head materials Stainless Steel
Liquid temperature range 4−60 °C (39.2−140 °F)
Gradient High pressure gradient (binary)
Leak management Yes
Wetted materials GFP (graphite fiber reinforced PTFE), sapphire, ruby, stainless steel, Zirconium oxide, DLC (Diamond-like carbon), Vespel®
Pump features Active pulsation compensation, RFID for automatic pump head detection, Integrated pressure sensor, Leak management, Piston seal wash, Purge valve (automatic)

Detailed information

Flow rate accuracy ± 0.25 %
Flow rate accuracy conditions measured at 1 ml/min at 1200 bar with water
Flow rate precision ≤ 0.04 % RSD or 0.008 min SD
Flow rate precision conditions whichever is greater
Gradient range 0–100 % in 0.1 % increments
Gradient accuracy ± 0.3 %
Gradient precision ≤ 0.1 % RSD or 0.01 min SD
Gradient minimum increment 0.1 %
Mixing volume 50 µl
Pump type Analytical UHPLC pump
Degasser Yes
Solvent selection valve 2 x 2 channels
Pulsation compensation Active pulsation compensation
Active piston seal wash Yes
Piston seal washing Yes
System protection Soft start, Pmin und Pmax are programmable
Pump Outlet thread Female UNF 10-32 (coned)
Pump head inlet (standard) UNF 1/4-28 Thread
Pump head outlet (standard) UNF 10-32 Thread


Interfaces LAN, Pin header connectors (Analog IN, Start In, Error IN)
Control LAN, Analog and event control, Mobile Control
Analog outputs 8 event outputs (TTL, OC, Relais) , 5 V and 24 V constant


Power supply 100–240 V; 50–60 Hz; Maximum power consumption 310 Watt
Dimensions 361 mm x 208.2 mm x 523 mm (W × H × D)
Weight 26.7 kg
Leak sensor Yes
Ambient conditions 4–40 °C (39.2–104 °F) Air humidity below 90 %, non-condensing

Certified Quality 

KNAUER is known for the quality of its products and has been certified several times. We produce high-tech laboratory instruments for research, routine analysis and production.
See all Quality certificates

In addition, we have extended documentation about all our products, including CE Declarations of Conformity.
See all CE Declarations of conformity

Innovation and quality - since 1962. Made in Germany.

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Technical data or prices are subject to change without notice. Prices may vary by country and do not include taxes, customs duties or delivery. All trademarks are the property of their respective owners.Our general terms and conditions apply: www.knauer.net/terms

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