EN DE

Why do reversed phase HPLC columns have an endcapping?

With an endcapping the influence of non derivatized silanol groups can be minimized. The endcapping reagent is generally a smaller silane than used for derivatisation. This treatment reduces the unwanted interaction of polar or charged analytes (acids, bases ect.) because the amount of available silanol groups is reduced.

Do you need more information?

Please contact us!

Follow us