EN DE

Can I run a reversed phase column with 100 % aqueous mobile phase?

It is definitely not recommended to run a common C18 column with pure aqueous mobile phase. Because of their length the linked chains have hydrophobic properties and might collapse if used with 100 % water.

As an alternative special columns with a hydrophilic/polar endcapping, like KNAUER Eurospher II C18 A, can be used.

 

 

We separate molecules and unite people.

Based in Berlin, KNAUER has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography systems and components, including:

Analytical HPLC / UHPLC
Preparative HPLC
Fast protein liquid chromatography (FPLC)
Multi-Column Chromatography / SMB
Osmometry

We are an established partner in science. Today and in the future.​​​​​​

Do you need more information?

Please contact us!

Follow us