Separation of Tricyclic Antidepressant drugs

Application No.: VPH0034J

Separation of Tricyclic Antidepressant drugs

ProntoSIL C18 AQ with its unique bonding technology has been especially developed for use with aqueous mobile phases with an organic content below 10%. ProntoSIL C18 AQ gives excellent peak shapes in these mobile phases resulting in enhanced selectivities. The advantages of the AQ-packings can be demonstrated in applications of polar analytes.

Technical Data


Method HPLC

Separation conditions

Mode RP
Substances Amitriptyline, Doxepin, Imipramine, Nortiptyline, Trimipramine
Key words Antidepressant, Drugs
CAS number 549-18-8, 1668-19-5, 50-49-7, 894-71-3, 739-71-9

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