ProntoSIL C18 ace-EPS belongs to a group of stationary RP supports with polar embedded groups. The packing is very stable over a wide pH range (pH 1-10). In addition, it offers a maximum of hydrophobicity combined with a maximum of polar selectivity. The silanophilic activity of the support is very low. Ultra strong basic compounds such as amitriptyline can be eluted from the column at neutral pH values with excellent symmetrical peak shapes. The main application area of these packings is the pharmaceutical industry where analytes often have basic or acidic groups. For the separation of these compounds, ProntoSIL C18 ace-EPS exhibits an enhanced polar selectivity compared to classical C18 stationary phases.
| Brand | ProntoSIL |
|---|---|
| Modification | C18 ace-EPS |
| Special characteristics | polar embedded phase, endcapped |
| Particle size | 5 µm |
| Pore size | 120 Å |
| Particle shape | spherical, totally porous |
| USP code | L1 |
| Length [mm] | 250 mm |
| Inner diameter [mm] | 4 mm |
| Application area | HPLC |
| Pore volume | n/a |
| Metal content | n/a |
| Carbon load | 18.5% |
| Recommended pH range | 1-10 |
| Density | n/a |
| Pressure rating | 400 bar |
| Temperature range | up to 40°C (up to 50 °C short term) |
| Specific surface area | 300 m²/g |
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