Eurospher C18 packing material can be universally used in different application areas and has been on the market for more than 15 years. The most often used material is the endcapped Eurospher 100 C18 for the reversed phase mode. The C18 phase can be considered for the determination of water soluble vitamins, steroids, catecholamines, sedatives and in many other application fields in the analytical as well as preparative range. The stationary phase is stable in a pH range of 2 - 8.5. Eurospher C18 is the workhorse for reversed phase applications.
Chromatograms of extracts from; a) blank plasma; b) plasma spiked with:; 1. 250 ng/ml metabolite; 2. 250 ng/ml amineptine; 3. 500 ng/ml internal standard; c) a patient plasma sample; obtained 45 min after taking a; 100 mg oral dose of; amineptine, spiked
|Key words||Drugs, Antidepressant drugs, human plasma, metabolite, Amineptine|
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