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Determination of Guaifenesin, Codein and Pseudoefedrin in cough syrup

Application No.: VPH0021J

Determination of Guaifenesin, Codein and Pseudoefedrin in cough syrup

Codeine, guaifenesin, and pseudoephedrine is a combination medicine used to treat stuffy nose, cough, sinus congestion, and chest congestion caused by allergies, the common cold, or the flu. Codeine is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex. Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth. Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). In this Application can you see a determination of Guaifenesin, Codein and Pseudoefedrin in cough syrup with Eurospher C18 packing material.

Technical Data

Application

Method HPLC

Separation conditions

Mode RP
Substances Codeine, Guaifenesin, Pseudoefedrin
Key words Codein, Guaifenesin, Pseudoefedrin
CAS number 76-57-3, 90-82-4, 93-14-1

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