KNAUER Blog – Fundamentals of High‑Performance LC

6 Articles

HPLC Basics ×

Oligos Made Easy _ Part 6 Column Navigator

How to Navigate Through the Jungle of Columns? Struggling to Find the Right Column for Your Oligos? Oligonucleotides are complex, long-chain molecules with a very high charge density and a wide variet...

AEX HPLC Basics IP-RP KNAUER Oligonucleotide Purification Oligos SEC SepapureOligo Size Exclusion

Sep 29, 2025

Oligos Made Easy _ Part 5 SEC

Size Matters: Mastering Size Exclusion for Oligos 💡Why Use SEC in the Oligo Revolution? Oligonucleotides are taking center stage in everything from cutting-edge therapeutics to diagnostics and synthet...

HPLC Basics KNAUER Oligonucleotide Purification Oligos SEC Size Exclusion

Sep 15, 2025

Oligos Made Easy _ Part 4 HILIC

Stick With Me:The Cool Chemistry of HILIC for Oligonucleotide Analysis 💡Why Use HILIC in the Oligo Revolution? Oligonucleotides are the workhorses behind gene therapies, diagnostics, and research break...

HILIC HPLC Basics Hydrophilic Interaction Liquid Chromatography KNAUER Oligonucleotide Analysis Oligos Separation

Sep 1, 2025

Oligos Made Easy _ Part 3 IP-RP

Pair With Me: The Sleek Science of Ion Pair (IP)-Reversed Phase (RP) Oligonucleotide Analysis 💡Why Purity Matters in the Oligo Revolution? In the high-stakes world of molecular biology, oligonucleotid...

HPLC Basics IP-RP Ion-Pair Reagent Ion-Pair Reversed Phase Mode KNAUER Oligonucleotide Analysis Oligos Separation

Aug 18, 2025

Oligos Made Easy _ Part 2 AEX

Charged for Action: The Hidden Secrets of AEX Oligonucleotide Analysis Oligonucleotides — short strands of DNA or RNA — are essential in modern molecular biology, playing a vital role in diagnostics, ...

AEX Anion Exchange HPLC Basics IEX Ion Exchange KNAUER Oligonucleotide Analysis Oligos Purification Separation

Aug 4, 2025

HPLC Basics

Understanding the Fundamentals of High-Performance Liquid Chromatography Liquid chromatography is a well-established technique for the separation of substances. High performance liquid chromatography ...

HPLC HPLC Basics

Feb 17, 2025