KNAUER Blog – Fundamentals of High‑Performance LC – AEX

7 Artikel

Oligos ×

Oligos Made Easy _ Part 7 Large Scale AEX

The Secret to Pure Oligos: Why Anion Exchange Chromatography Rules at Scale Oligonucleotide therapeutics are on the rise. More and more short DNA and RNA drugs are entering clinical development and ev...

AEX Anion Exchange HPLC HPLC Basics IEX Ion Exchange Oligonucleotide Oligos Purification Separation

13.10.2025

Oligos Made Easy _ Part 6

How to navigate through the jungle of columns? 💡Struggling to Find the Right Column for Your Oligos? Oligonucleotides are complex, long-chain molecules with a very high charge density and a wide varie...

AEX HPLC Basics IP-RP KNAUER Oligonucleotide Purification Oligos SEC SepapureOligo Size Exclusion

29.09.2025

Oligos Made Easy _ Part 5

Size Matters:Mastering Size Exclusion for Oligos 💡Why Use SEC in the Oligp Revolution? Oligonucleotides are taking center stage in everything from cutting-edge therapeutics to diagnostics and syntheti...

HPLC Basics KNAUER Oligonucleotide Purification Oligos SEC Size Exclusion

15.09.2025

Oligos Made Easy _ Part 4

Stick With Me:The Cool Chemistry of HILIC for Oligonucleotide Analysis 💡Why Use HILIC in the Oligo Revolution? Oligonucleotides are the workhorses behind gene therapies, diagnostics, and research break...

HILIC HPLC Basics Hydrophilic Interaction Liquid Chromatography KNAUER Oligonucleotide Analysis Oligos Separation

01.09.2025

Oligos Made Easy _ Part 3

Pair With Me: The Sleek Science of Ion Pair (IP)-Reversed Phase (RP) Oligonucleotide Analysis 💡Why Purity Matters in the Oligo Revolution? In the high-stakes world of molecular biology, oligonucleotid...

HPLC Basics IP-RP Ion-Pair Reagent Ion-Pair Reversed Phase Mode KNAUER Oligonucleotide Analysis Oligos Separation

18.08.2025

Oligos Made Easy _ Part 2

Charged for Action: The Hidden Secrets of AEX Oligonucleotide Analysis Oligonucleotides — short strands of DNA or RNA — are essential in modern molecular biology, playing a vital role in diagnostics, ...

AEX Anion Exchange HPLC Basics IEX Ion Exchange KNAUER Oligonucleotide Analysis Oligos Purification Separation

04.08.2025

Oligos Made Easy _ Part 1 Overview

The Hitchhiker´s Guide to Creating Oligonucleotides from Start to Finish Back in 2020 we came up with an innovative system for making lipid nanoparticles (LNP), and it's completely changed things here...

Innovation KNAUER Oligonucleotide Analysis Oligonucleotide Synthesis Oligos Purification

21.07.2025