Injection Valves

Engineered for a wide range of chromatography and dosing applications.

Backpressure Range

up to 1200 bar 

Flow Rates

up to 1000 ml/min depending on bore size and capillary connection


Application Areas

From analytical to prep with 1/16", 1/8", 1/4" connection

Port Number

6, 8, 10

Wetted Material 

DLC coated stainless steel for high pressure applications, PEEK for  biocompatibility


Internal volume

0.3 - 4.0 mm bore size

HPLC valves for sample injection

The injection of samples into the system is the most common application of switching valves. Whether operated manually by a lever or automated by an electric actuator, the valve in the injection position directs the fluid flow through a sample loop previously filled in the loading position. At the same time, the chromatography data system receives a signal about the switching. After this injection of the sample or completion of the chromatography run, the valve is switched back to the loading position and the sample loop can be filled with sample again.


The valve type usually used for this task is a 6-port 2-position valve (also referred to as 6-port 3-channel valve) such as our AZURA V 4.1 Ultra High Pressure Valve. The same valve can also be used to switch between two columns, if both have to be used frequently and a laborious column change is to be avoided.


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Manual or automated?

With KNAUER AZURA® V 4.1 Valves, the user decides how a sample is injected.

KNAUER Product Selection Guide
Instruments, components and services for (U)HPLC, Prep-LC, FPLC and Osmometry.

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