KNAUER Blog – Fundamentals of High‑Performance LC – AEX

4 Articles

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Oligos Made Easy _ Part 7 Large Scale AEX

The Secret to Pure Oligos: Why Anion Exchange Chromatography Rules at Scale Oligonucleotide therapeutics are on the rise. More and more short DNA and RNA drugs are entering clinical development and ev...

AEX Anion Exchange HPLC HPLC Basics IEX Ion Exchange Oligonucleotide Oligos Purification Separation

Oct 13, 2025

Oligos Made Easy _ Part 4 HILIC

Stick With Me:The Cool Chemistry of HILIC for Oligonucleotide Analysis 💡Why Use HILIC in the Oligo Revolution? Oligonucleotides are the workhorses behind gene therapies, diagnostics, and research break...

HILIC HPLC Basics Hydrophilic Interaction Liquid Chromatography KNAUER Oligonucleotide Analysis Oligos Separation

Sep 1, 2025

Oligos Made Easy _ Part 3 IP-RP

Pair With Me: The Sleek Science of Ion Pair (IP)-Reversed Phase (RP) Oligonucleotide Analysis 💡Why Purity Matters in the Oligo Revolution? In the high-stakes world of molecular biology, oligonucleotid...

HPLC Basics IP-RP Ion-Pair Reagent Ion-Pair Reversed Phase Mode KNAUER Oligonucleotide Analysis Oligos Separation

Aug 18, 2025

Oligos Made Easy _ Part 2 AEX

Charged for Action: The Hidden Secrets of AEX Oligonucleotide Analysis Oligonucleotides — short strands of DNA or RNA — are essential in modern molecular biology, playing a vital role in diagnostics, ...

AEX Anion Exchange HPLC Basics IEX Ion Exchange KNAUER Oligonucleotide Analysis Oligos Purification Separation

Aug 4, 2025