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Fully automated solid-phase oligonucleotide synthesis

Supports standard modifications (OMe, MOE, thiolation, spacer, GalNAc and much more)

Combined flowrates up to 
500 mL/min​ 
Recycling loop for efficient coupling steps

Easy in-house maintenance with low cost Lifetime Support

Synthesis Scales from 100 µmol to 
30 mmol

One platform for Research and GMP Production

System Overview

What's included …

A set of two optimised 

AZURA® 2.1L pumps

Two valve drives VU 4.1

One UV detector (MWD)

Pressure unit (pressure reduction and split)

Two tubing sets

One conductivity detector within the recycle loop

GL45 caps for reagents

Two Assistants (ASM) with multiple selection valves and one recycle valve

Software optimised for oligonucleotide synthesis

High-Quality Oligonucleotide Synthesis – Fast, Reliable, and Cost-Effective

Established Flow-Design

Ready for GMP

Avoid any cross-contamination using ACN wash-lines next to all phosphoramidites

Material certificates available

12 phosphoramidite positions

21 CFR GAMP5 compliant software

Recycle using pump B to ensure high coupling efficiencies with low amidite equivalents

Regulatory support (IQ/OQ/PQ)

Monitor your synthesis with up to 4 different wavelengths and conductivity detection within the recycle line

 

Waste separation for green chemistry

 

User-customizable flowchart

 

Insights from the field

Come visit us at conferences and workshops!


GO TO EVENTS



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