The demand of pure cannabidiol (CBD) is increasing and therefore methods are needed that allow purification of CBD in high purity from different kind of samples i.e. cannabis extract, paste or oil. Preparative HPLC is a well-established method for purification of target substances from natural substrates in high purities and was therefore applied for this task. In this application a preparative HPLC method was developed for purification of CBD from a commercial CBD rich oil. CBD was purified with high purity and recovery thus increasing the purity from 71.6% to 94.5%.
CBD capsules and seeds
photo: pixabay/CBD-Infos-com
| Method | HPLC |
|---|---|
| Mode | RP |
| Substances | Cannabinoids |
| Key words | Cannabis, hemp, purification, scale-up, preparative LC, CBD purification, CBDV, CBG, CBD, CBN, Δ9-THC, CBL, CBC |
| CAS number | 24274-48-4, 2808-33-5, 13956-29-1, 521-35-7, 1972-08-3, 21366-63-2, 20675-51-8 |
| Version | Version 1 I 08/2020 |
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