Why do I need a precolumn?

A precolumn or also called guard column protects the main column of plugging and contamination by samples and mobile phase. We recommend using precolumns, integrated or stand-alone, because they are easy to replace and it generates less charge for you than replacing the main column. But: A precolumn never substitutes the necessary sample pretreatment.
The lifetime of a precolumn is limited, it is a consumable, and contingent upon the analysed matrix and how good the sample preparation is.

We separate molecules and unite people.

Based in Berlin, KNAUER has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography systems and components, including:

Analytical HPLC / UHPLC
Preparative HPLC
Fast protein liquid chromatography (FPLC)
Multi-Column Chromatography / SMB

We are an established partner in science. Today and in the future.​​​​​​

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