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Which kind of solvent and modifiers can I use in polar organic mode?

Suitable mobile phases for operation in polar organic mode include 2-propanol, ethanol, methanol and acetonitrile. Modifiers include N,N-diethylamine (DEA) for basic samples, trifluoroacetic acid (TFA) for acidic samples. It is recommendable to minimize the use of a modifier. Typical use is 0.1 % and maximum concentration should not exceed 0.5%.

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