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Isocratic separation of the Digoxin and Digitoxin series of Glycosides

Application No.: VPH0019J

Isocratic separation of the Digoxin and Digitoxin series of Glycosides

Digoxin and Digitoxin are a cardiac glycoside. Cardiac glycosides are organic compounds containing a glycoside (sugar) that act on the contractile force of the cardiac muscle. Because of their potency in disrupting the function of the heart, most are extremely toxic. These glycosides are found as secondary metabolites in several plants, and in some insects, such as the milkweed butterflies, that consume the plants. In this Application can you see a separation of cardiac glycoside with Eurospher C18 packing material.

Technical Data

Application

Method HPLC

Separation conditions

Mode RP
Substances Digoxigenin, Digoxigenin monodigitoxoside, Digoxigenin bisdigitoxoside, Digoxin, Digitoxigenin, Digitoxigenin monodigitoxoside, Digitoxigenin bisdigitoxoside, Digitoxin
Key words Drugs, Glycosides, Digitalis Glycosides, Digoxin, Digitoxin, cardiac glycoside
CAS number 1672-46-4, 5352-63-6, 5297-05-2, 20830-75-5, 143-62-4, 18404-43-8, 16479-50-8,71-63-6

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