EN DE

Determination of Paracetamol and by-products

Application No.: VPH0025J

Determination of Paracetamol and by-products

ProntoSIL C8 ace-EPS belongs to a new group of stationary RP supports with polar embedded groups. The packing is very stable over a wide pH range (pH 1-10). In addition, it offers a combination of hydrophobicity with a maximum of polar selectivity. The silanophilic activity of the support is very low. Ultra strong basic compounds can be eluted from the column at neutral pH values with excellent symmetrical peak shapes. The main application area of these packings is the pharmaceutical industry where analytes often have basic or acidic groups.
  • Chromatogram VPH0025J

    1. 4-Aminophenol; 2. Paracetamol; 3. N-(2-hydroxyphenyl)acetamide; 4. N-(4-hydroxyphenyl)propanamide; 5. N-phenylacetamide; 6. 1-(4-hydroxyphenyl)ethanone oxime; 7. 1-(2-hydroxyphenyl)ethanone; 8. Chloracetanilide; 9. 4-Nitrophenol

  • Pharma Applications

Technical Data

Application

Method HPLC

Separation conditions

Mode RP
Substances Paracetamol, N-(2-hydroxyphenyl)acetamide, N-(4-hydroxyphenyl)propanamide, N-phenylacetamide, Chloracetanilide, 1-(4-hydroxyphenyl)ethanone oxime, 1-(2-hydroxyphenyl)ethanone, 4-Aminophenol, 4-Nitrophenol
Key words Paracetamol, Drugs
CAS number 103-90-2, 614-80-2, 1693-37-4, 103-84-4, 539-03-7, 34523-34-7, 118-93-4, 123-30-8, 100-02-7

Documents and more information

Do you need more details or application support?

We are happy to help you

+49 30 809727-0

applications@knauer.net

Follow us on: