Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. Standard grade neomycin is composed of a number of related compounds including neomycin A (neamine), neomycin B (framycetin), neomycin C, and a few minor compounds found in much lower quantities. Neomycin B is the most active component in neomycin followed by neomycin C and neomycin A. Neomycin A is an inactive degradation product of the C and B isomers. The quantities of these components in neomycin vary from lot-to-lot depending on the manufacturer and manufacturing process.
acidic sample solution; (ointment); 1 Imp. 1; 2 Imp. 2; 3 Imp. 3; 4 Neomycin sulphate C; 5 Neomycin sulphate B
|Substances||Neomycin sulphate B, Neomycin sulphate C|
|Key words||Neomycin sulphate, aminoglycoside antibiotics, ELSD|
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