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Can I switch between NP and RP mode with only one HPLC system?

Yes it is generally possible to switch from NP to RP mode with one HPLC system but we recommend using KNAUER pumps for NP because the check valves are optimized for the use of normal phase solvents. When using only one system it has to be considered that the system components have to be flushed with isopropanol as an intermediate step.

We separate molecules and unite people.

Based in Berlin, KNAUER has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography systems and components, including:

Analytical HPLC / UHPLC
Preparative HPLC
Fast protein liquid chromatography (FPLC)
Multi-Column Chromatography / SMB
Osmometry

We are an established partner in science. Today and in the future.​​​​​​

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