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AZURA® Pilot SMB System
Article No.: A29501

One Pilot System solution for SMB and capture SMB

The AZURA Pilot SMB System A29501 is optimized for the separation of binary mixtures in gram to kilogram-scale. Its special emphasis is put on the continuous operation mode and high productivity. The system configuration consists of four Pump 2.1L and seven 8-port multiposition valves integrated into four AZURA Assistans ASM 2.1L. Our user friendly software PurityChrom® MCC and the required IT hardware are included too. This system is our standard Pilot SMB configuration and is optimized to bring success on a wide range of applications both the separation of smal molecules and the purification of proteins via capture SMB. A maximum pressure of 100 bar, eight columns and a flowrate of up to 500 ml/min allows you to do a separation on columns up to 50 mm ID.

Choose your operation mode!

With our SMB-Systems you can easily switch between different operation modes:

Classical SMB Chromatography

The standard configuration is designed to run classical SMB separations. You can easily switch between different zone configurations. To switch from a classical 2:2:2:2 to a 1:3:3:1 configuration you just need to click one button in our software PurityChrom MCC. Other configurations can be chosen too.

Capture SMB

The flexible design of the SMB system allows you to run continuous FPLC purification after minor changes to the system. Use AZURA Lab SMB as your step to the future of biopurification and run your downstream process with the highest productivity and lowest costs. Parallel Batch Chromatography Just add detectors to the the System and run batch runs parallel or use the system for single batch runs. You could use an eight column setup to run four separations parallel for example.* The most flexible SMB System in the world Use a wide range of different upgrade options or just add a detector to build up a SMB chromatography system suits perfectly to your needs. Do you want to change the wetted parts? Contact us to get more information!

Available Upgrade-Kits

With our preconfigured Upgrade-Kits you can upgrade your SMB chromatography system very easily and build up the system you need.

Upgrade-KitArt. No
FlowmeterWith the CORI-Flow M14 you can monitor you SMB process and react instantly on every influence to the separation process (Single device or set of four flowmeter for full system monitoring).


A29803 (set of four)

HeatingAdd an oven to your SMB and take full control over the column temperature. Can be used for eight KNAUER columns up to 250 x 50 mm.A29900

*additional equipment required

Technical Data

AZURA SMB systems

Max. flow rate 500 ml/min
Recommended flow rate 2-200 ml/min
Maximum delivery pressure [psi] 1450 psi
Maximum delivery pressure [bar] 100 bar
Maximum delivery pressure [MPa] 10 MPa
Column configuration 2:2:2:2
Operating modes classical SMB, MCCP*, batch*
Supported software packages PurityChrom® MCC

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Technical data are subject to change without notice.
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