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AZURA Lab SMB System
Article No.: A29002

System solution for ultra high pressure and high temperature continuous chromatography

This AZURA Lab SMB System is optimized for very challenging multicolumn separation of binary mixtures of smal molecules in several hundred mg scale. The SMB System A29002 is the only ultra high pressure SMB System on the market. It consists of seven 6-multiposition valves and four AZURA P 4.1S included in four Assitants ASM 2.1L.* The high pressure range up to 400 bar allows to use column material down to 3 µm. Addionally it is possible to heat the columns up to 60°C. Running this system in an 3-Zone process allows you to succeed in even the most difficult separation tasks for small molecules. This system is not optimized for the separation of biomolecules or standard separations of binary mixures of small molecules. Therefore have a look at our AZURA® SMB Lab System

Classical SMB Chromatography

The standard configuration is designed to run classical SMB separations. You can easily switch between different zone configurations. To switch from a classical 2:2:2:2 to a 1:3:3:1 configuration you just need to click one button in our software PurityChrom MCC. Other configurations can be chosen too.


The flexible design of the SMB system allows you to run continuous FPLC purification after minor changes to the system. Use AZURA Lab SMB as your step to the future of biopurification and run your downstream process with the highest productivity and lowest costs.

The most flexible SMB System in the world Use a wide range of different upgrade options or just add a detector to build up a SMB chromatography system suits perfectly to your needs. Do you want to change the wetted parts? Contact us to get more information!

Available Upgrade-Kits

With our preconfigured Upgrade-Kits you can upgrade your SMB chromatography system very easily and build up the system you need.

System and process control: A29800 (one CORI-FLOW), A29801 (four CORI-FLOW)

Heating and column organisation: A29900 (oven), A29901 (column holder ID 50), A29902 (for columns with 8, 16 or 20mm ID)

Batch-Ugrade: A29601 (stainless steel), A29600 (bio-compatible)




Parallel Batch Chromatography Just add detectors to the the System and run batch runs parallel or use the system for single batch runs. You could use an eight column setup to run four separations parallel for example.**


* Columns and the AZURA Click (A70089 + accesory) are not included. **additional equipment required

Technical Data

AZURA SMB systems

Max. flow rate 10 ml/min
Recommended flow rate 0.5-4 ml/min
Maximum delivery pressure [psi] 5800 psi
Maximum delivery pressure [bar] 400 bar
Maximum delivery pressure [MPa] 40 MPa
Column dimensions up to 30 mm ID
Column configuration 1:2:2:1
Operating modes classical SMB, MCCP*, batch*
Supported software packages PurityChrom® MCC

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Technical data are subject to change without notice.
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