C18 stationary phase for the analysis of more polar and hydrophilic compounds in reversed phase mode (USP L1). Silica gel based columns with C18 modification with hydrophilic endcapping.
Ultra pure, spherical high performance HPLC phase based on silica gel
Polar, monomeric C18 (Octadecyl) modification, polar endcapping, with 10 % carbon content (~ 50 % endcapping)
Separation mechanism: Hydrophobic and polar interaction
C18 A phase with alternative, more polar selectivity, suited for the use with pure aqueous mobile phases, 50 % endcapping and resulting 10 % carbon content, outstanding mechanical and chemical stability, suited for analytical as well as semi preparative and preparative applications
C18 A phase based on ultra-pure silica gel (purity > 99 %), metal content < 10 ppm, pH-stability 2 - 8, pore size 100 A, particle size 2 μm, 3 μm, 5 μm, 10 μm (15 μm, 20 – 45 μm on request)
polar endcapped C18 phase for water soluble and polar analytes, 100 % aqueous eluents for analysis of very polar compounds, basic pharmaceutical ingredients, water soluble vitamins, catecholamines as well as organic acids.
Ultra pure, spherical high performance HPLC phase based on silica gel
Polar, monomeric C18 (Octadecyl) modification, polar endcapping, with 14 % carbon content
ProntoSIL C18 AQ with its unique bonding technology has been especially developed for the use in aqueous mobile phases with an organic content below 10%. Standard stationary phases with conventional bondings give very poor peak shapes under these chromatographic conditions due to the collapse of C18-brushes in aqueous eluents. ProntoSIL C18 AQ gives excellent peak shapes in these mobile phases resulting in enhanced selectivities. The advantages of the AQ-packings can be demonstrated in applications of polar analytes. The C18 AQ-bonding type is fully endcapped and available in several particle sizes.
Ultra pure, spherical high performance HPLC phase based on silica gel
Polar, monomeric C18 (Octadecyl) modification, polar endcapping, with 17 % carbon content
In addition to ProntoSIL C18 AQ, ProntoSIL C18 AQ PLUS has been developed for the use in aqueous mobile phases with an organic content below 10%. In comparison to ProntoSIL C18 AQ, ProntoSIL C18 AQ PLUS shows an enhanced stability at low pHs down to pH 1. Also the packing shows excellent peak shapes in pure aqueous eluents but differs in shape selectivity compared to ProntoSIL C18 AQ. The application field for this support is mainly in combinatorial chemistry where the standard separation conditions are fast gradients from 0 - 100% organic and where the mobile phases include 0.1 %TFA.
