Si columns for Normal Phase and HILIC applications
Unmodified Silica gel materials were the first ones used for chromatography. This is the reason the mode is called "Normal phase" (NP). They are still used in HPLC, although Reversed Phase (NP) is by far the most often used HPLC mode today.
A wide range of porous Si materials is available, characterized by
- surface area
- pore size
- particle size
- metal content