Refractive index detector

Article Nr.: ADD31

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The AZURA RID 2.1L is a sensitive and competitively priced differential refractometer. It is suitable for detecting compounds with little or no UV activity such as alcohols, sugars, lipids or polymers. This instrument is designed for use in analytical HPLC (high performance liquid chromatography) as well as for GPC (gel permeation chromatography) applications.

The intelligently designed optical unit with advanced temperature control ensures high sensitivity, fast baseline stabilization, and excellent reproducibility. Furthermore, the long-life LED, highly pressure resistant flow cell, improved safety features and enhanced diagnostics functions guarantee easy handling and minimal maintenance.

The wide linear dynamic range and 10 ml/min maximum flow rate make the AZURA RID 2.1L the perfect choice for most laboratory tasks.

This detector can be controlled with OpenLAB® EZChrom, ClarityChrom®, Chromeleon® and PurityChrom® Bio software, as well as from the AZURA Mobile Control app (stand-alone operation), via LAN or through analog input/output, allowing it to be integrated into almost any LC system.

Learn more in our video:

More details in our technical poster:

Key features

  • Temperature controlled optical unit
  • Long-life LED
  • Pressure resistant flow cell (5 bar)
  • Wide linear dynamic range
  • Selection of software drivers
  • AZURA Neo electronic platform
Detector type

Analytical refractive index detector

Light source

Long-life LED

Refractive index range

1.00 - 1.75 RIU


± 2.5 nRIU


200 nRIU/h


> 1000 µRIU

Temperature control

OFF, 30 - 55 °C (1 °C increment)

Maximum flow rate

10 ml/min (pure water)

Time constants

0.00 / 0.01 / 0.02 / 0.05 / 0.1 / 0.2 / 0.5 / 1.0 / 2.0 / 5.0 / 10.0 s


Full range

Flow cell

5 bar back pressure resistance

Flow cell included

Flow cell volume

15 µl

Wetted materials

Stainless steel / fused silica / PTFE / PEEK

Maximum data rate

100 Hz (LAN)/20 Hz (Analog)


2 x LAN (RJ-45, dual IP-stack), USB (service only), multi-pin connector, analog (cinch connector)


Mobile Control, software, event control, analog, terminal protocol


Error (IN), Start (IN), Autozero, Flush (IN)


Event 1, Start (OUT), Error (OUT), + 5 V, 24 V Valve

Analog outputs

1 x 0- 2.5 V scalable, 20 bit, offset adjustable

Technical parameters

Detailed report including operating hours, light source operating hours


Mobile Control (optional)

Ambient conditions

Temperature range: 4 - 40 °C, 39.2 - 104 °F, Humidity: below 90 % noncondensing

Power supply

100 - 240 V, 50 - 60 Hz, 65 W


361 x 158 x 523 mm (W x H x D)


10.8 kg

Leak sensor

Yes (internal and external leak management)

Optional accessories

Mobile Control

AZURA Detector RID 2.1L user manual

AZURA Detector RID 2.1L user manual, V6750

Refractive Index Detector Kit

Analysis of non-UV absorbing substances with AZURA RID 2.1

AZURA Detektor RID 2.1L Benutzerhandbuch

AZURA Detektor RID 2.1L Benutzerhandbuch, V6750

Performance Verification of AZURA systems with refractive index detector (OpenLab)

This application note is a guideline describing step-by-step a compact performance verification (PV) of AZURA® Analytical HPLC systems including a refractive index detector, using a reversed phase (RP) column and a standard test solution (VSP0012N)

List of supported instruments in KNAUER chromatography systems List of supported devices in chromatography data systems

Device support in KNAUER CDS / KNAUER device support in 3rd party software

Refractive Index Detector Kit

Analysis of non-UV absorbing substances with AZURA RID 2.1

Mobile Control

Software controlling AZURA devices/ system
including 10" tablet


Tool kit AZURA

tool kit for systems with PEEK or precut capillaries


Accessory kit AZURA RID 2.1L

included in shipkit


Technical data are subject to change without notice.
All trade names and registered trademarks are the property of their respective owners.



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