AZURA Pilot Prep LC 250 HPG

Binary high pressure gradient system with max. flow rate of 250 ml/min

Article Nr.: 744203110

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The AZURA Pilot Prep LC 250 HPG system is a complete binary high pressure gradient (HPG) HPLC system for the purification of samples in the laboratory scale. It is designed and optimized for the purification of milligram to gram samples. This system proposal consists of two preparative HPLC pumps, a UV/VIS detector and a freely customizable combination module.

The AZURA P 2.1L pump covers a wide flow rate range and pressure capabilities. In the current setup, it supports max. pressures up to 225 bar at flow rates up to 100 ml/min (200 bar from 150 - 250 ml/min). The integrated automatic recognition of the pump head with RFID technology allows fast adaptions of the pump for various applications. The HPG setup enables the precise formation of binary gradients. Besides, ternary and quaternary gradients are accessible by integration of additional preparative pumps.

The AZURA UVD 2.1L represents a UV/VIS detector with a variable single wavelength for the detection of fast eluting peaks.

The system is completed by an AZURA assistant ASM 2.1L for preparative HPLC. The assistant module can be customized to individual requirements. For example, to enable automatic injection and fraction collection, the assistant module contains three integrated modules:

  • Large sample volumes can be applied automatically via the integrated injection valve and feed pump.
  • The integrated fractionation valve enables sample fractionation without an additional fraction collector.
  • Under isocratic conditions, the consumption of solvent can be reduced by the use of solvent recycling at high flow rates. Peak recycling allows improving the resolution of a pair of closely eluting solutes (e.g., a pair of enantiomers) by automated repeated processing of the peaks.

The AZURA Preparative HPLC system comes with an eluent tray for safe storage of eluent bottles and an integrated leak management system with sensors.

VertexPlus AX columns (20 mm and 30 mm ID) can be attached with an optional AZURA mounting bracket at both sides of each AZURA element. A leak sensor and the capillary guidance as well as the optional Mobile Control with touch screen facilitate the safe and user friendly operation. Modern design with completely demountable fronts turn the system into a visual highlight.

Key features
  • BinComplete high pressure gradient preparative HPLC system for purification of mg and gram samples
  • Pump offers a wide range of flow rates (0.1 – 250 ml/min)
  • Automatic recognition of the pump head with RFID technology
  • UV/VIS detector with a variable single wavelength
  • Fractionation valve for fraction collection, solvent and peak recycling
  • Injection valve and feed pump for automated injection of large sample volumes
  • Optional Mobile Controle allows direct control and monitoring of all integrated modules
  • Leakage protection
  • Customizable

Preparative HPLC pump with 250 ml/min pump head, stainless steel



Preparative HPLC pump with 250 ml/min pump head, stainless steel


Pump head inlet

for preparative pumps, 1/4" (NPT) stainless steel


Pump head inlet

for preparative pumps, 1/4" (NPT) stainless steel


Inlet-bushing kit for pump head inlet AZURA

Solvent Filter
1/4"-PTFE Tubing
up to 250 ml/min


AZURA UV/VIS Detector UVD 2.1L

190 - 750 nm, variable single wavelength UV/VIS detector


AZURA ASM 2.1L for Preparative HPLC

Combination module:
12 port multi position valve, 1/8" connectors,
6 port 3 channel injection valve, 1/8" connectors, and
Pump with pressure sensor, 50 ml pump head


KNAUER VariLoop S for 1/8" tubings

stainless steel, 1/8", 10 ml


Mounting bracket AZURA L

for preparative sample loop


AZURA Eluent tray E 2.1L

Eluent tray for up to 6 x 1000 ml bottles, (delivery without bottles),
or 4 x 2.5 l bottles,
or 2 x 5 l bottles,
or 1 x 10 l bottle


Mobile Control

Software controlling AZURA devices/ system
including 10" tablet


Mobile Control Tablet Mount

Universal tilt and swivel tablet mount


Chromatography Workstation

for PurityChrom® and ClarityChrom® with 24" monitor, international edition


Router 8-Port, EU-version

Router to connect all AZURA Instruments via LAN and WLAN


Preparative UV Flow Cell

variable path length and variable volume, 1/8", 200 bar, stainless steel


ClarityChrom Prep 7.2

single instrument license one time base


Tool kit AZURA

tool kit for systems with 1/8" capillaries made of stainless steel


AZURA Capillary Start-up kit

1/8", stainless steel


Capillary, stainless steel, 1/16"

stainless steel, 1/16" OD, 1 mm ID, 300 cm length


AZURA Preparative System Installation Card

AZURA Installation Card Preparative, V6800A

AZURA Preparative System Installation Card

AZURA Installation Card Preparative, V6800

AZURA Pre-Installation Guide

AZURA Pre-Installation Guide, V6802

Mounting bracket AZURA L

for axial compressible columns with 20 mm ID


Torque wrench

Open-jaw plug-in excluded


Product riser AZURA

28 mm height


Installation Box Kit

Box for small parts, KNAUER file folder and support sticker


Technical data are subject to change without notice.
All trade names and registered trademarks are the property of their respective owners.

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